First base I build in midwest Turkey, which gets me all of Europe (except Iceland, Svalbard and the part of Greenland that belongs to Europe), damn near all of the Middle East, and parts of Russia and Africa as well. That lets me keep four of eight sponsors happy right off the bat. This base gets 2 workshops, 4 labs and 2 interceptors to begin with. Later on, I may take down some of the labs for more interceptors, since two interceptors have trouble bringing down harvesters.
The second base is in northern Thailand, getting me almost all of Asia (except Japan, unfortunately) and part of Oceania, including India. This base gets no research, but 4 workshops (maybe 5, but 4 would be neater as far as use of living quarters is concerned).
I plan for all of my bases to have garrisons and interceptors. I don't plan to use SAM bases much (unless I later find out I need to) and I don't plan to spend any base slots on base defense weapons. Having soldiers in every base spreads the precious EXP rather thin, though, so maybe I'll limit myself to 16-24 soldiers total which I hire to whichever base I currently need them at. But I'm pretty far from having to worry about that - it's only May and I just got the second base's radar operational.
For all of you who like to play around with base layouts, check out my Easy Radar Rangefinding mod in the mods section. It makes trying out base locations a lot more convenient. I used it to work out the layout in the attached screenshot, which I plan to use. It's designed to maximize detection coverage on all the landmasses, not just population hotspots. I may still shift the order of base building around, and I'll probably move the russia base a little more northeast if I build it that late, to get less redundant landmass and cover more ocean instead. Hmm... maybe I should also drop a radar tower on Hawaii... that's bound to be in the Cities list, right?
(About Dragons: How difficult are they to keep fed? Does each unit of fuel they have in their status screen require one unit of antimatter?)
(About starting aircraft: which do you prefer, Stilettos or Saracens, and why?)
(About aircraft parameters: Is the 'damage' parameter in the script files the hitpoint value? Does the 'range' parameter determine weapon range? I thought the weapon alone determines the range...)